Begona Heras

occupation: researcher

official website: scholars.latrobe.edu.au/bheras

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Articles 45

Date

Title

Authors

2021-02-10

Antivirulence DsbA inhibitors attenuate <i>Salmonella enterica</i> serovar Typhimurium fitness without detectable resistance

Yaoqin Hong, Begona Heras, Makrina Totsika
2019-02-26

The atypical thiol-disulfide exchange protein α-DsbA2 from Wolbachia pipientis is a homotrimeric disulfide isomerase

Patricia M Walden, Andrew E Whitten, Begona Heras, Jennifer L. Martin
2019-04-29

Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules

Jason J. Paxman, Matthew J. Sullivan, Santosh Panjikar, Andrew E Whitten, Lendl Tan, Minh-Duy Phan, Christine L Gee, Glen C Ulett, Mark A. Schembri, Begona Heras, Danilo G Moriel
2019-10-18

The Fragment-Based Development of a Benzofuran Hit as a New Class of Escherichia coli DsbA Inhibitors

Luke F Duncan, Geqing Wang, Olga V Ilyichova, Martin J. Scanlon, Begona Heras, Belinda Abbott
2019-12-02

Molecular and structural insights into an asymmetric proteolytic complex (ClpP1P2) from Mycobacterium smegmatis

Jason J. Paxman, Kaye N Truscott, Begona Heras, David A. Dougan
2019-12-11

A Molecular Chameleon for Mapping Subcellular Polarity in an Unfolded Proteome Environment

Pramod Subedi, Elizabeth Hinde, Jason J. Paxman, Weisan Chen, Begona Heras, Wallace W.H. Wong, Yuning Hong
2019-07-31

Differential homotypic and heterotypic interactions of antigen 43 (Ag43) variants in autotransporter-mediated bacterial autoaggregation

Grégory JUBELIN, Philippe Ruiz, Xavier Bailly, Etienne Dague, Jason J. Paxman, Begona Heras
2019-08-23

The Scs disulfide reductase system cooperates with the metallochaperone CueP in Salmonella copper resistance

Jason J. Paxman, Zhiguang Xiao, Begona Heras
2019-05-07

CrmA orthologs from diverse poxviruses potently inhibit caspases-1 and -8, yet cleavage site mutagenesis frequently produces caspase-1-specific variants

Begona Heras, Christine Hawkins
2018-01-01

Production, biophysical characterization and initial crystallization studies of the N- and C-terminal domains of DsbD, an essential enzyme in Neisseria meningitidis

Andrew E Whitten, Jason J. Paxman, Martin J. Scanlon, Charlene M Kahler, Begona Heras
2018-09-04

Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens

Jason J. Paxman, Stephen J Headey, Bradley Doak, Charlene M Kahler, Martin J. Scanlon, Begona Heras
2017-01-01

Bioinformatics Tools and Resources for Analyzing Protein Structures

Jason J. Paxman, Begona Heras
2017-10-12

Autotransporter Adhesins in Escherichia coli Pathogenesis

Suresh Mathivanan, Jason J. Paxman, Begona Heras
2017-12-14

INHIBITION OF DIVERSE DsbA ENZYMES IN MULTI-DsbA ENCODING PATHOGENS.

Jason J. Paxman, Jennifer L. Martin, Martin J. Scanlon, Begona Heras
2016-07-16

Targeting Bacterial Dsb Proteins for the Development of Anti-Virulence Agents

Jason J. Paxman, Martin J. Scanlon, Begona Heras
2016-12-28

Structural and Biochemical Characterization of Chlamydia trachomatis DsbA Reveals a Cysteine-Rich and Weakly Oxidising Oxidoreductase

Signe Christensen, Morten K Grøftehauge, Karl Byriel, Emily J Furlong, Begona Heras, Jennifer L. Martin, Roisin Mcmahon
2016-03-15

Molecular and Structural Characterization of a Novel Escherichia coli Interleukin Receptor Mimic Protein

Scott A. Beatson, Glen C Ulett, Mark A. Schembri, Begona Heras, Jason J. Paxman, Lendl Tan, Matthew J. Sullivan, Samantha J. Dando, Danilo G Moriel
2015-02-01

Targeting virulence not viability in the search for future antibacterials

Begona Heras, Martin J. Scanlon, Jennifer L. Martin
2015-11-26

Sent packing: protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibility

Roisin Mcmahon, Begona Heras, Craig J Morton, Martin J. Scanlon, Jennifer L. Martin
2014-01-07

The antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping

Begona Heras, Makrina Totsika, Jason J. Paxman, Russell Jarrott, Matthew Perugini, Andrew E Whitten, Mark A. Schembri
2014-05-23

Structure of the Acinetobacter baumannii dithiol oxidase DsbA bound to elongation factor EF-Tu reveals a novel protein interaction site

Morten K Grøftehauge, Begona Heras, Jennifer L. Martin
2014-12-30

Application of fragment-based screening to the design of inhibitors of Escherichia coli DsbA

Biswaranjan Mohanty, Olga V Ilyichova, Makrina Totsika, Bradley Doak, Sofia Caria, James Horne, Stephen J Headey, Jennifer L. Martin, Begona Heras, Martin J. Scanlon
2014-01-02

Unraveling the redox properties of the global regulator FurA from Anabaena sp. PCC 7120: disulfide reductase activity based on its CXXC motifs

Begona Heras
2013-09-20

Rv2969c, essential for optimal growth in Mycobacterium tuberculosis, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfide oxidases

Begona Heras, David P. Fairlie, Jennifer L. Martin
2013-10-29

Structural insights into the role of the cyclic backbone in a squash trypsin inhibitor

Kathryn P Greenwood, Gordon J King, K. Johan Rosengren, Begona Heras, Jennifer L. Martin, David Craik, Norelle L Daly
2013

Comparative Sequence, Structure and Redox Analyses of Klebsiella pneumoniae DsbA Show That Anti-Virulence Target DsbA Enzymes Fall into Distinct Classes

Biswaranjan Mohanty, Begona Heras, David P. Fairlie, Martin J. Scanlon, Jennifer L. Martin
2012-09-13

The 1.2 Å resolution crystal structure of TcpG, the Vibrio cholerae DsbA disulfide-forming protein required for pilus and cholera-toxin production

Begona Heras, Kai-En Chen, Martin J. Scanlon, Jennifer L. Martin
2012-01-15

Characterisation of a cell wall-anchored protein of Staphylococcus saprophyticus associated with linoleic acid resistance

Makrina Totsika, Scott A. Beatson, Mark A. Schembri, Nathan P King, Nouri L Ben Zakour, Begona Heras, Mark Shepherd
2010-03-16

Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium

Begona Heras, Makrina Totsika, Russell Jarrott, Timothy J Wells, Alastair G McEwan, Mark A. Schembri
2010-04-30

Expression and crystallization of SeDsbA, SeDsbL and SeSrgA from Salmonella enterica serovar Typhimurium

Makrina Totsika, Mark A. Schembri, Begona Heras
2009-12-03

In vivo oxidative protein folding can be facilitated by oxidation-reduction cycling

Begona Heras, Jennifer L. Martin, Mehmet Berkmen
2009-02-09

DSB proteins and bacterial pathogenicity

Makrina Totsika, Mark A. Schembri, Begona Heras, Martin J. Scanlon, Jennifer L. Martin

Human - wd:Q57306599

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