Flavia Valtorta

1957 -

country of citizenship: Italy

languages spoken, written or signed: Italian, English

educated at: University of Milan, The Rockefeller University

occupation: pharmacologist

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Articles 93

Date

Title

Authors

2020-10-14

Proline-rich transmembrane protein 2 (PRRT2) regulates the actin cytoskeleton during synaptogenesis

Fabio Benfenati, Flavia Valtorta
2020-11-10

Pharmacological antagonism of kainate receptor rescues dysfunction and loss of dopamine neurons in a mouse model of human parkin-induced toxicity

Flavia Valtorta, Jenny Sassone
2019-05-01

Constitutive Inactivation of the PRRT2 Gene Alters Short-Term Synaptic Plasticity and Promotes Network Hyperexcitability in Hippocampal Neurons

Bruno Sterlini, Nicola Forte, Enrico Castroflorio, Flavia Valtorta, Jin-Wu Tsai, Anna Fassio
2018-03-01

A novel topology of proline-rich transmembrane protein 2 (PRRT2): Hints for an intracellular function at the synapse.

Flavia Valtorta
2018-05-23

Reduced peripheral availability of tryptophan and increased activation of the kynurenine pathway and cortisol correlate with major depression and suicide

Gabriella Gobbi, Flavia Valtorta, Stefano Comai
2017-04-05

Serotonin Dysfunction, Aggressive Behavior, and Mental Illness: Exploring the Link Using a Dimensional Approach

Mirko Manchia, Stefano Comai, Flavia Valtorta
2017-09-01

The synaptic function of parkin

Flavia Valtorta
2017-09-05

eIF4B phosphorylation at Ser504 links synaptic activity with protein translation in physiology and pathology

Barbara Bettegazzi, Fabrizia Claudia Guarnieri, Flavia Valtorta, Michele Simonato, Daniele Zacchetti
2017-09-30

Impaired GABAB-mediated presynaptic inhibition increases excitatory strength and alters short-term plasticity in synapsin knockout mice

Flavia Valtorta
2017-12-01

APache Is an AP2-Interacting Protein Involved in Synaptic Vesicle Trafficking and Neuronal Development.

Enrico Castroflorio, Fabrizia Claudia Guarnieri, Caterina Michetti, Mattia Bramini, Annalisa Savardi, Fabrizia Cesca, Angela Bachi, Anna Fassio, Flavia Valtorta, Jonathan Wren
2017-03-01

eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures

Christopher G. Proud, Chiara Verpelli, Luca Murru, Fabrizia Claudia Guarnieri, Michael M Poe, Michael Rajesh Stephen, Maksym Kopanitsa, Francesco Rusconi, Maura Francolini, Flavia Valtorta, Angela Bachi
2017-10-21

Synapsin I deletion reduces neuronal damage and ameliorates clinical progression of experimental autoimmune encephalomyelitis

Roberto Furlan, Fabrizia Claudia Guarnieri, Riccardo Fesce, Davide Pozzi, Eugenio F Fornasiero, Michela Matteoli, Luca Muzio, Flavia Valtorta
2017-09-11

A novel SYN1 missense mutation in non-syndromic X-linked intellectual disability affects synaptic vesicle life cycle, clustering and mobility.

Fabrizia Claudia Guarnieri, Andrea Raimondi, Michela Matteoli, Patrizia D'Adamo, Flavia Valtorta
2017-01-01

A Method to Culture GABAergic Interneurons Derived from the Medial Ganglionic Eminence

Elisa Savino, Flavia Valtorta
2016-01-21

A Novel Topology of Proline-rich Transmembrane Protein 2 (PRRT2): HINTS FOR AN INTRACELLULAR FUNCTION AT THE SYNAPSE

Bruno Sterlini, Enrico Castroflorio, Flavia Valtorta, Luca Maragliano
2016-12-20

The PRRT2 knockout mouse recapitulates the neurological diseases associated with PRRT2 mutations

Caterina Michetti, Enrico Castroflorio, Nicola Forte, Bruno Sterlini, Floriana Fruscione, Flavia Valtorta, Federico Zara
2016-09-10

PRRT2: from Paroxysmal Disorders to Regulation of Synaptic Function

Flavia Valtorta, Federico Zara
2016-04-01

Sphingosine-1-Phosphate (S1P) Impacts Presynaptic Functions by Regulating Synapsin I Localization in the Presynaptic Compartment

Flavia Antonucci, Martina Gabrielli, Ilaria Prada, Paola Giussani, Paola Viani, Flavia Valtorta, Michela Matteoli, Claudia Verderio, Elisabetta Menna
2016-03-24

PRRT2 Is a Key Component of the Ca(2+)-Dependent Neurotransmitter Release Machinery

Enrico Castroflorio, Bruno Sterlini, Cosimo Prestigio, Fabrizia Claudia Guarnieri, Marta Orlando, Federico Zara, Anna Fassio, Flavia Valtorta
2014-08-15

GRP78 clustering at the cell surface of neurons transduces the action of exogenous alpha-synuclein

Andrea Mescola, Hanako Tsushima, Sharada Tilve, Claudio Canale, Flavia Valtorta, Evelina Chieregatti
2014-05-01

Phosphorylation of synapsin I by cyclin-dependent kinase-5 sets the ratio between the resting and recycling pools of synaptic vesicles at hippocampal synapses

Daniel Gitler, Anna Fassio, Flavia Valtorta
2014-08-15

Distinct temporal hierarchies in membrane and cytoskeleton dynamics precede the morphological polarization of developing neurons.

Eugenio F Fornasiero, Flavia Valtorta
2013-02-12

Epileptogenic Q555X SYN1 mutant triggers imbalances in release dynamics and short-term plasticity

Anna Rocchi, Francesco Paonessa, Fabrizia Cesca, Marta Orlando, Flavia Valtorta, Patrick Cossette
2013-08-15

SYN2 is an autism predisposing gene: loss-of-function mutations alter synaptic vesicle cycling and axon outgrowth

Anna Fassio, Amélie Piton, Guy A. Rouleau, Flavia Valtorta, Laurent Mottron, Julie Gauthier, Patrick Cossette, Lysanne Patry, Anna Corradi, Manuela Fadda, Maxime Cadieux-Dion, Fabio Benfenati
2013-10-22

REST/NRSF-mediated intrinsic homeostasis protects neuronal networks from hyperexcitability

Anna Fassio, Davide Pozzi, Andrea Contestabile, Francesco Paonessa, Pellegrino Lippiello, Flavia Valtorta
2012-08-01

Synapsins contribute to the dynamic spatial organization of synaptic vesicles in an activity-dependent manner

Eugenio F Fornasiero, Marta Orlando, Flavia Valtorta
2012-12-29

Autism-related behavioral abnormalities in synapsin knockout mice

Francesca Managò, Flavia Valtorta
2012-02-24

Synaptic and extrasynaptic origin of the excitation/inhibition imbalance in the hippocampus of synapsin I/II/III knockout mice

Fabrizia Cesca, Thierry Nieus, Flavia Valtorta
2012-03-07

Kainate induces mobilization of synaptic vesicles at the growth cone through the activation of protein kinase A

Christophe Mulle, Claudia Verderio, Elisabetta Menna, Flavia Antonucci, Flavia Valtorta, Michela Matteoli
2012-04-01

Site-specific synapsin I phosphorylation participates in the expression of post-tetanic potentiation and its enhancement by BDNF

Thierry Nieus, Flavia Valtorta
2011-06-01

The synapsins: multitask modulators of neuronal development

Flavia Valtorta, Davide Pozzi, Eugenio F Fornasiero
2011-03-25

SYN1 loss-of-function mutations in autism and partial epilepsy cause impaired synaptic function.

Anna Fassio, Amélie Piton, Guy A. Rouleau, Davide Pozzi, Flavia Valtorta, Laurent Mottron, Julie Gauthier, Patrick Cossette, Lysanne Patry, Judith St-Onge, Anna Corradi, Manuela Fadda, Fabio Benfenati, Caroline Meloche

Human - wd:Q57656015

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