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Restoring mitochondrial DNA copy number preserves mitochondrial function and delays vascular aging in mice

pengarang

Martin R. Bennett

1962 -

Michael P. Murphy

1963 -

diterbitkan dalam: Aging Cell

tanggal publikasi: 2018-05-09

bahasa: Inggris

subyek utama: biologi sel, Ageing, DNA mitokondria, mitokondria

Cites articles 30

Date

Judul

Pengarang

2017-09-28

Mitochondrial Respiration Is Reduced in Atherosclerosis, Promoting Necrotic Core Formation and Reducing Relative Fibrous Cap Thickness.

Martin R. Bennett, Michael P. Murphy
2016-03-15

Age-Related and Heteroplasmy-Related Variation in Human mtDNA Copy Number

Burkhard Madea, Alexander Hübner, Mark Stoneking
2016-02-01

Central Artery Stiffness in Hypertension and Aging: A Problem With Cause and Consequence

C. Alberto Figueroa
2015-12-01

Mitochondrial dysfunction and longevity in animals: Untangling the knot
2014-06-06

Mitochondrial DNA copy number in peripheral blood cells declines with age and is associated with general health among elderly

Jonas Mengel-From, Mikael Thinggaard, Christine Dalgård, Kirsten Kyvik, Kaare Christensen
2014-07-01

Control of mitochondrial integrity in ageing and disease

Radek Szklarczyk
2014-04-01

Aging synaptic mitochondria exhibit dynamic proteomic changes while maintaining bioenergetic function

Phillip Purnell
2014-01-01

Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells

Joel N. Meyer
2013-11-11

Overexpression of Twinkle-helicase protects cardiomyocytes from genotoxic stress caused by reactive oxygen species

Jaakko Pohjoismäki, Johnny Kim, Thomas Braun
2013-07-10

Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species through effects on smooth muscle cells and monocytes and correlates with higher-risk plaques in humans

Michael P. Murphy, Martin R. Bennett, Murray Clarke, Antonio Vidal-Puig
2013-04-01

Enhanced immunity in slowly aging mutant mice with high mitochondrial oxidative stress

Siegfried Hekimi
2012-09-04

Age- and calorie restriction-related changes in rat brain mitochondrial DNA and TFAM binding

Anna Picca, Vito Pesce, Christiaan Leeuwenburgh
2012-03-28

Peroxisome proliferator-activated receptor-γ protects against vascular aging

Frank M Faraci
2011-11

The mitochondrial DNA helicase TWINKLE can assemble on a closed circular template and support initiation of DNA synthesis

Maria Falkenberg, Géraldine Farge, Claes Gustafsson
2010

A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans

Siegfried Hekimi
2010-08-12

DNA damage links mitochondrial dysfunction to atherosclerosis and the metabolic syndrome

Martin R. Bennett, Antonio Vidal-Puig, Michael P. Murphy, Julian L Griffin
2010-03-01

Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis

Christodoulos I. Stefanadis, Charalambos Vlachopoulos
2010-04-22

High mitochondrial DNA copy number has detrimental effects in mice

Emil Ylikallio, Henna Tyynismaa
2008-12-11

The overexpression of major antioxidant enzymes does not extend the lifespan of mice

Holly Van Remmen, Arlan G. Richardson, Jan Vijg
2008-03-02

DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice

Jonathan Wanagat, Gregory C Kujoth, Peter S. Rabinovitch
2007-06-20

The mitochondrial transcription factor TFAM coordinates the assembly of multiple DNA molecules into nucleoid-like structures

Santiago Costantino, Jeffrey M Mativetsky, Peter Grütter
2007-04-23

Proinflammatory profile within the grossly normal aged human aortic wall

Gaia Spinetti, Edward Lakatta, Frank D Kolodgie, Renu Virmani, Robert E Monticone, Gianfranco Pintus
2006-05-11

Matrix metalloproteinase 2 activation of transforming growth factor-beta1 (TGF-beta1) and TGF-beta1-type II receptor signaling within the aged arterial wall

Gaia Spinetti, Edward Lakatta, Gianfranco Pintus
2005-11-21

Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice

Sjoerd Wanrooij, Emil Ylikallio, Johannes N Spelbrink, Henna Tyynismaa
2004-12-15

Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number

Anu Jalanko, Neil Ashley, Johannes N Spelbrink, Ian Holt, Henna Tyynismaa, Joanna Poulton
2004-06-16

Reconstitution of a minimal mtDNA replisome in vitro

Maria Falkenberg
2004-05-01

Premature ageing in mice expressing defective mitochondrial DNA polymerase

Anna Wredenberg, Johannes N Spelbrink, Sebastian Gidlöf, Howard Jacobs
2004-03-11

Mitochondrial transcription factor A regulates mtDNA copy number in mammals.

Maria Falkenberg, Kjell Hultenby, Nils-Göran Larsson
2001-11-01

Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans

Siegfried Hekimi
1998-02-01

Differential expression of mitochondrial DNA replication factors in mammalian tissues

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