Wolfgang F. Richter

educated at: University of Marburg

occupation: researcher

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Articles 27

Date

Title

Authors

2020-06-24

Protease-activation using anti-idiotypic masks enables tumor specificity of a folate receptor 1-T cell bispecific antibody

Martina Geiger, Johannes Sam, Wolfgang F. Richter, Carina Hage, Florian M Freimoser, Matthias E Lauer, Henning Stahlberg, Sebastian Kobold, Christian Klein, Stefan Endres
2019-02-15

High-Throughput, Sensitive LC-MS Quantification of Biotherapeutics and Biomarkers Using Antibody-Free, Peptide-Level, Multiple-Mechanism Enrichment via Strategic Regulation of pH and Ionic and Solvent Strengths

Wolfgang F. Richter, Jun Qu
2019-12-01

Are Biotransformation Studies of Therapeutic Proteins Needed? Scientific Considerations and Technical Challenges

Simone Schadt, Simon Hauri, Martin R Edelmann, Roberto Villaseñor, Franz Schuler, Wolfgang F. Richter
2018-01-28

Biotherapeutics in non-clinical development: Strengthening the interface between safety, pharmacokinetics-pharmacodynamics and manufacturing

A Baumann, Wolfgang F. Richter
2018-04-05

Hematopoietic cells as site of first-pass catabolism after subcutaneous dosing and contributors to systemic clearance of a monoclonal antibody in mice.

Wolfgang F. Richter, Hans Peter Grimm
2018-05-01

CD20-TCB with Obinutuzumab Pretreatment as Next-Generation Treatment of Hematologic Malignancies

Wolfgang F. Richter, Florian M Freimoser, Christian Klein
2018-10-01

Subcutaneous Administration of Biotherapeutics: An Overview of Current Challenges and Opportunities

Wolfgang F. Richter
2017-07-25

Reproductive and developmental toxicology studies with gantenerumab in PS2APP transgenic mice

Paul C Barrow, Wolfgang F. Richter
2017-04-13

Tissue Distribution of a Therapeutic Monoclonal Antibody Determined by Large Pore Microdialysis

Wolfgang F. Richter, Hartmut Derendorf
2016-08-27

Non-clinical Safety Evaluation of Biotherapeutics - Challenges, Opportunities and new Insights

A Baumann, Wolfgang F. Richter
2016-11-18

In Vivo Biotransformation of the Fusion Protein Tetranectin-Apolipoprotein A1 Analyzed by Ligand-Binding Mass Spectrometry Combined with Quantitation by ELISA

Wolfgang F. Richter
2016-01-18

Immunogenicity, Inflammation, and Lipid Accumulation in Cynomolgus Monkeys Infused with a Lipidated Tetranectin-ApoA-I Fusion Protein

Wolfgang F. Richter
2015-11-24

Neonatal Immune Tolerance Induction to Allow Long-Term Studies With an Immunogenic Therapeutic Monoclonal Antibody in Mice

Carole Bourquin, Wolfgang F. Richter
2014-01-22

Non-clinical pharmacokinetic/pharmacodynamic and early clinical studies supporting development of a novel subcutaneous formulation for the monoclonal antibody rituximab

Wolfgang F. Richter
2014-08-06

Subcutaneous absorption of biotherapeutics: knowns and unknowns

Wolfgang F. Richter
2014-04-19

New challenges and opportunities in nonclinical safety testing of biologics

A Baumann, Roy Forster, Wolfgang F. Richter
2013

Subcutaneous versus intravenous administration of rituximab: pharmacokinetics, CD20 target coverage and B-cell depletion in cynomolgus monkeys

Wolfgang F. Richter
2013-03-25

The effects of interleukin-6 signal blockade on immune system, reproductive and skeletal development in juvenile mice

Wolfgang F. Richter
2013-11-20

6-Alkoxy-5-aryl-3-pyridinecarboxamides, a new series of bioavailable cannabinoid receptor type 1 (CB1) antagonists including peripherally selective compounds.

Wolfgang F. Richter
2012-01-01

Gantenerumab: a novel human anti-Aβ antibody demonstrates sustained cerebral amyloid-β binding and elicits cell-mediated removal of human amyloid-β

Wolfgang F. Richter
2012-03-01

Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration

Charles Boswell, Dimitry M Danilenko, Wolfgang F. Richter
2012-05-23

Mechanistic determinants of biotherapeutics absorption following SC administration

Wolfgang F. Richter
2011-07-21

Potential errors in the volume of distribution estimation of therapeutic proteins composed of differently cleared components

Wolfgang F. Richter
2007-07-01

Analysis of erlotinib and its metabolites in rat tissue sections by MALDI quadrupole time-of-flight mass spectrometry

Wolfgang F. Richter
2006-02-28

The distribution pattern of radioactivity across different tissues in quantitative whole-body autoradiography (QWBA) studies

Wolfgang F. Richter
2003-01-01

Design of experiment (DOE) methods maximize information from a minimal number of animals in special cases of preclinical bioavailability testing

Wolfgang F. Richter
1998-04-01

Animal pharmacokinetics and interspecies scaling of Ro 25-6833 and related (lactamylvinyl)cephalosporins

Wolfgang F. Richter

Human - wd:Q74457423

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