Patricia Steeg

1954 -

country of citizenship: United States of America

occupation: biomedical scientist, cancer researcher

Patricia Steeg is a cancer researcher working in the field of breast cancer metastasis, and was the first person to discover the NME1 gene, which spreads breast cancer to other parts of the body. Source: Wikipedia (en)

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Articles 92

Date

Title

Authors

2021-10-21

The mitochondrially-localized nucleoside diphosphate kinase D (NME4) is a novel metastasis suppressor

Teresita Padilla-Benavides, Béatrice Nawrocki-Raby, Christelle Machon, David Bernard, Uwe Schlattner, Patricia Steeg
2020-05-09

A HER2 Antibody Drug Conjugate Controls Growth of Breast Cancer Brain Metastases in Hematogenous Xenograft Models, with Heterogeneous Blood-Tumor Barrier Penetration Unlinked to a Passive Marker

Michael G Overstreet, Patricia Steeg
2020-07-08

Brain Metastasis Cell Lines Panel: a public resource of organotropic cell lines

Manuel Valiente, Amanda Van Swearingen, Adrienne Boire, Paula D Bos, Dai Fukumura, Sheri L Holmen, Rakesh Jain, Nicola R Sibson, Damir Varešlija, Amos Bairoch, Patricia Steeg
2020-04-09

Temozolomide in secondary prevention of HER2-positive breast cancer brain metastases

Alexandra S Zimmer, Patricia Steeg
2019-02-18

MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer

Patricia Steeg
2019-03-01

A framework for the development of effective anti-metastatic agents

Robin L Anderson, David R. Jones, Mark Sullivan, John F Marshall, Jacqui A Shaw, Patricia Steeg
2019-11-04

Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis

Daniela P Freitas, Peter R. Oxley, Brian D. Dill, Haiying Zhang, Etienne Meylan, Bruno Costa-Silva, Shizhen Emily Wang, Charles Rudin, Héctor Peinado, Cyrus M Ghajar, Maria de Sousa, David Pisapia, David Lyden, David R Jones, Shahin Rafii, Patricia Steeg
2019-02-22

Estradiol induces BDNF/TrkB signaling in triple-negative breast cancer to promote brain metastases

María J Contreras-Zárate, David Ryan Ormond, Diana M Cittelly, Patricia Steeg
2019-07-16

Metastasis Suppressors NME1 and NME2 Promote Dynamin 2 Oligomerization and Regulate Tumor Cell Endocytosis, Motility, and Metastasis

Patricia Steeg
2018-05-04

Limited fibrosis accompanies triple-negative breast cancer metastasis in multiple model systems and is not a preventive target.

Patricia Steeg
2018-07-13

Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases

Brunilde Gril, Anurag N Paranjape, Wojciech Kloc, Ewa Izycka-Swieszewska, Renata Duchnowska, Rafał Pęksa, Priscilla K Brastianos, Gary T Pauly, Jacek Jassem, Wojciech Biernat, Emily Hua, Naema Nayyar, Emma Dolan, Joel P. Schneider, William Douglas Figg, Sr., Patricia Steeg
2017-11-06

SCDT-11. ASTROCYTIC S1P3 SIGNALING MODULATES BLOOD-TUMOR BARRIER PERMEABILITY IN BRAIN METASTASES

Renata Duchnowska, Patricia Steeg
2017-11-06

SCDT-12. STUDY OF ROLE OF ASTROCYTIC S1P3 IN REGULATING BLOOD-BRAIN/TUMOR BARRIER PERMEABILITY

Patricia Steeg
2017-11-06

TMIC-19. ASTROCYTIC S1P3 SIGNALING MODULATES BLOOD-TUMOR BARRIER PERMEABILITY IN BRAIN METASTASES

Renata Duchnowska, Patricia Steeg
2017-11-06

TMIC-37. THE MICROENVIRONMENT OF A YOUNGER BRAIN IS MORE PERMISSIVE FOR BREAST CANCER BRAIN METASTASIS

Patricia Steeg
2017-11-06

TMIC-34. STUDY OF ROLE OF ASTROCYTIC S1P3 IN REGULATING BLOOD-BRAIN/TUMOR BARRIER PERMEABILITY

Patricia Steeg
2016-05-31

Alterations in Pericyte Subpopulations Are Associated with Elevated Blood-Tumor Barrier Permeability in Experimental Brain Metastasis of Breast Cancer

Wojciech Kloc, Ewa Izycka-Swieszewska, Priscilla K Brastianos, Renata Duchnowska, Emily Hua, Naema Nayyar, Paul R Lockman, Patricia Steeg
2016-08-19

Vinorelbine Delivery and Efficacy in the MDA-MB-231BR Preclinical Model of Brain Metastases of Breast Cancer

Patricia Steeg
2016-10-10

Therapeutics for Brain Metastases, v3.

Patricia Steeg
2015-01-06

Predicting early brain metastases based on clinicopathological factors and gene expression analysis in advanced HER2-positive breast cancer patients

Yesim Gokmen-Polar, Konrad Wojdan, Jacek Jassem, Wojciech Biernat, George Sledge, Renata Duchnowska, Patricia Steeg
2015-08-30

Analysis of radiation therapy in a model of triple-negative breast cancer brain metastasis

Sudhanshu Shukla, Patricia Steeg
2014-03-14

A BRCA1 deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity

Steven A. Narod, Patricia Steeg
2014-06-19

DNA double-strand break repair genes and oxidative damage in brain metastasis of breast cancer

Yesim Gokmen-Polar, Tomasz Trojanowski, Jacek Jassem, Wojciech Biernat, George Sledge, Tomasz Mandat, Renata Duchnowska, Patricia Steeg
2014-03-14

Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner

Stephen M. Hewitt, Jacek Jassem, Wojciech Biernat, Renata Duchnowska, Patricia Steeg
2014-05-06

Toward a drug development path that targets metastatic progression in osteosarcoma

Richard G Gorlick, Danny R Welch, Malcolm A Smith, Sharon A. Savage, Nita L Seibel, Peter J. Houghton, Jeffrey Trent, Lee J Helman, Eugenie S Kleinerman, Glenn Merlino, Paul S Meltzer, Katherine A Janeway, Stephen J Withrow, Beverly A Teicher, Peter Adamson, Brenda J Weigel, R Lor Randall, Mark Krailo, Patricia Steeg
2014-07-11

Capecitabine and lapatinib uptake in surgically resected brain metastases from metastatic breast cancer patients: a prospective study

Viviane Tabar, Patricia Steeg
2014-08-03

Identification and validation of genes with expression patterns inverse to multiple metastasis suppressor genes in breast cancer cell lines

Natasha J. Caplen, Yesim Gokmen-Polar, George Sledge, Patricia Steeg
2013-08-12

Nm23-h1 binds to gelsolin and inactivates its actin-severing capacity to promote tumor cell motility and metastasis

Patricia Steeg
2013-10-16

Massively parallel sequencing reveals an accumulation of de novo mutations and an activating mutation of LPAR1 in a patient with metastatic neuroblastoma

Peter Johansson, Rajesh Patidar, J. Silvio Gutkind, Patricia Steeg
2013-01-09

A rapid ultra HPLC-MS/MS method for the quantitation and pharmacokinetic analysis of 3-deazaneplanocin A in mice

Patricia Steeg
2013-04-12

Pazopanib inhibits the activation of PDGFRβ-expressing astrocytes in the brain metastatic microenvironment of breast cancer cells

Patricia Steeg
2013-07-26

Breast cancer metastasis: issues for the personalization of its prevention and treatment

Patricia Steeg

Human - wd:Q81240009

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