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The importance of B cell receptor isotypes and stereotypes in chronic lymphocytic leukemia

author

Elisa Ten Hacken

Paolo Ghia

published in: Leukemia

date of publication: 2018-12-16

main subject: chronic lymphocytic leukemia

Cites articles 148

Date

Title

Authors

2018-01-19

Targeting B cell receptor signalling in cancer: preclinical and clinical advances.
2018-06-26

The Light Chain IgLV3-21 Defines a New Poor Prognostic Subgroup in Chronic Lymphocytic Leukemia: Results of a Multicenter Study

Tom Smith, Emerence Crompot, Marek Mráz, Pauline Robbe, Adam Burns, David Bruce, Jan Philippé, Bruno Verhasselt
2018-02-26

Depth and durability of response to ibrutinib in CLL: 5-year follow-up of a phase II study.

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2018-08-09

The BTK Inhibitor ARQ 531 Targets Ibrutinib-Resistant CLL and Richter Transformation

Bonnie K Harrington, Brian Schwartz
2018-02-12

Final results of a phase 1b study of the safety and efficacy of the PI3Kδ inhibitor acalisib (GS-9820) in relapsed/refractory lymphoid malignancies.
2018-03-09

IgM and IgD B cell receptors differentially respond to endogenous antigens and control B cell fate.

Mark Noviski, Lee Ann Garrett-sinha, Julie Zikherman
2017-05-01

CXCR4 signaling and function require the expression of the IgD-class B-cell antigen receptor

Martin Becker
2017-09-12

Pathogen-specific B-cell receptors drive chronic lymphocytic leukemia by light-chain-dependent cross-reaction with autoantigens

Nereida Jiménez de Oya, Jessica Fioravanti, Dimitar Efremov, Hassan Jumaa, Paolo Ghia, Luca G. Guidotti, Matteo Iannacone
2017-06-09

Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia

Claudia Minici, Paolo Ghia, Massimo Degano
2017-07-27

Calreticulin as a novel B-cell receptor antigen in chronic lymphocytic leukemia

Alessandra Ferrajoli, Zeev Estrov, William G Wierda, Michael J. Keating, Jan A Burger, Elisa Ten Hacken, Ekaterina Kim, Paolo Ghia
2017-11-22

Signaling pathways and immune evasion mechanisms in classical Hodgkin lymphoma

Margaret A Shipp
2017-01-12

Binding of CLL subset 4 B-cell receptor immunoglobulins to viable human memory B lymphocytes requires a distinctive IGKV somatic mutation

Ten Feizi
2017-01-26

Leukemia cell proliferation and death in chronic lymphocytic leukemia patients on therapy with the BTK inhibitor ibrutinib

Hagop Kantarjian, Alessandra Ferrajoli, William G Wierda, Susan O'Brien, Michael J. Keating, Dominik Wodarz, Mariela Sivina, Xuelin Huang, Jan A Burger, Nicholas Chiorazzi
2017-01-11

Ibrutinib Therapy Increases T Cell Repertoire Diversity in Patients with Chronic Lymphocytic Leukemia

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Ibrutinib treatment improves T cell number and function in CLL patients

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2017-01-03

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The evolutionary landscape of chronic lymphocytic leukemia treated with ibrutinib targeted therapy

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2017-10-09

MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia

Deanna H Wong, Lorena Fontán
2017-06-23

Combined BTK and PI3Kδ Inhibition with Acalabrutinib and ACP-319 Improves Survival and Tumor Control in CLL Mouse Model

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Extended Treatment with Single-Agent Ibrutinib at the 420 mg Dose Leads to Durable Responses in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

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IgD attenuates the IgM-induced anergy response in transitional and mature B cells

Anselm Enders, Zahra Sabouri, Peter Humburg, Keisuke Horikawa, Clara Young, Matthew A Field, Joanne H Reed, Chris Goodnow
2016-06-14

Surface IgM expression and function are associated with clinical behavior, genetic abnormalities, and DNA methylation in CLL

Peter Johnson, Freda K. Stevenson, Francesco Forconi, Marta Larrayoz, Matthew J Rose-Zerilli, Graham Packham
2016-03-21

IL-4 enhances expression and function of surface IgM in CLL cells

Peter Johnson, Mark S Cragg, Francesco Forconi, Freda K. Stevenson, Marta Larrayoz, Adam Linley, Andrew Davies, Graham Packham, Andrew J Steele, Matthew D Blunt
2016-05-25

IL-4 rescues surface IgM expression in chronic lymphocytic leukemia

Benchang Guo, Nicholas Chiorazzi
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Functional Differences between IgM and IgD Signaling in Chronic Lymphocytic Leukemia

Paolo Ghia, Alessandra Ferrajoli, Zeev Estrov, William G Wierda, Susan O'Brien, Michael J. Keating, Jan A Burger, Mariela Sivina, Elisa Ten Hacken, Ekaterina Kim, Federico Caligaris-Cappio
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B Cell Anergy Modulated by TLR1/2 and the miR-17∼92 Cluster Underlies the Indolent Clinical Course of Chronic Lymphocytic Leukemia Stereotyped Subset #4.

Achilles Anagnostopoulos, Paolo Ghia, Stavroula Ntoufa, Marta Muzio
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Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors

Florence Nguyen-Khac, Chrysoula Belessi, Anastasia Hadzidimitriou, Nicholas Chiorazzi, Marta Larrayoz, Carsten Utoft Niemann, Alba Navarro, Karla Plevová, Elías Campo, Gianluca Gaidano, Panagiotis Baliakas, Zadie Davis, Frédéric Davi, Kostas Stamatopoulos, David G Oscier, Andreas Agathangelidis, Lesley-Ann Sutton, Lydia Scarfò, Larry Mansouri, Lone Bredo Pedersen, Anton W Langerak, Theodoros Moysiadis, Evangelia Stalika, Myriam Boudjoghra, Alice F Muggen, Jonathan C Strefford, Paolo Ghia, ERIC, the European Research Initiative on CLL
2016-08-29

Evidence of shared epitopic reactivity among independent B-cell clones in chronic lymphocytic leukemia patients

Selena Mimmi, Marco Rossi, Antonio Lupia, Francesco Albano, Giuseppe Fiume, Camillo Palmieri
2016-11-01

Ibrutinib efficacy and tolerability in patients with relapsed chronic lymphocytic leukemia following allogeneic HCT.

Peter Hillmen, Susan O'Brien, Michael J. Keating, John C Byrd, Martin Dyer, Samantha M Jaglowski, Steven Coutre, Fong Clow, Lori Styles
2016-01-26

Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia

Joseph A. Fraietta, Marco Ruella, David M Barrett, Simon F Lacey, Jan Melenhorst, Shannon E McGettigan, Changfeng Zhang, Alexandria P. Cogdill, Saar Gill, David L. Porter, Meixiao Long, Bruce L. Levine, Carl H. June, Marcela V. Maus

Article - wd:Q90569013

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