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Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors

author

Hans-Heinrich Hoffmann

William M Schneider

Francisco J Sánchez-Rivera

Joseph M Luna

Alison W. Ashbrook

Yadira M Soto-Feliciano

Jérémie Le Pen

Inna Ricardo-Lax

Eleftherios Michailidis

Scott W. Lowe

Margaret R MacDonald

John T Poirier

Charles M. Rice

1952 -

date of publication: 2020-09-11

main subject: SARS-CoV-2

Cites articles 41

Date

Title

Authors

2020-03-04

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

Christian Drosten
2020-08-14

The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro

Purushothama Rao Tata
2020-03-16

Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2

William Martin
2020-04-30

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

David E Gordon, Kirsten Obernier, Kris M White, Matthew J O'Meara, Danielle L Swaney, Tia A Tummino, Ruth Hüttenhain, Alicia L Richards, Beril Tutuncuoglu, Helene Foussard, Maya Modak, Minkyu Kim, Paige Haas, Benjamin J Polacco, Hannes Braberg, Melanie J Bennett, Merve Cakir, Ferdinand Roesch, Thomas Vallet, Alice Mac Kain, Elena Moreno, Zun Zar Chi Naing, Yuan Zhou, Shiming Peng, Ying Shi, Ziyang Zhang, Wenqi Shen, James E Melnyk, John S Chorba, Kevin Lou, Shizhong A Dai, Inigo Barrio-Hernandez, Danish Memon, Christopher J P Mathy, Tina Perica, Kala Bharath Pilla, Sai J Ganesan, Ramachandran Rakesh, Sara Brin Rosenthal, Lorenzo Calviello, Srivats Venkataramanan, Jose Liboy-Lugo, Stephanie A Wankowicz, Cassandra Koh, Nastaran Sadat Savar, Quang Dinh Tran, Djoshkun Shengjuler, Michael C O'Neal, David J Broadhurst, Saker Klippsten, Phillip P. Sharp, Nicole A Wenzell, Hao-Yuan Wang, Raphael Trenker, Janet M Young, Theodore L Roth, Julia Noack, Mathieu Hubert, Oren S Rosenberg, David A Agard, Michael Emerman, Natalia Jura, Mark von Zastrow, Eric Verdin, Christophe d'Enfert, Matthew P. Jacobson, Harmit Singh Malik, Trey Ideker, Charles S Craik, James S Fraser, John Gross, Bryan L. Roth, Tanja Kortemme, Pedro Beltrao, Marco Vignuzzi, Adolfo García-Sastre, Kevan M. Shokat, Nevan Krogan, Lisa Miorin, Melanie Ott, Jeffrey Z Guo, Robyn M. Kaake, Michael J McGregor, Daniel J. Saltzberg, Robert M. Stroud, Kliment A Verba, Andrej Šali, Brian K. Shoichet, Jacqueline M Fabius, Jack Taunton
2020

Drug Repurposing Screens Reveal FDA Approved Drugs Active Against SARS-CoV-2
2020-04-28

Disparate temperature-dependent virus – host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium

Philip V'kovski, Bastien Mangeat, Joern Pezoldt, Melle Holwerda, Annika Kratzel, Rune Hartmann, Vincent Gardeux, Bart Deplancke, Volker Thiel, Ronald Dijkman
2020-08-10

The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients
2020-06-26

COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis

Robert Lorenz Chua, Soeren Lukassen, Saskia Trump, Bianca P Hennig, Daniel Wendisch, Fabian Pott, Loreen Thürmann, Florian Kurth, Julia Kazmierski, Felix Machleidt, Johannes Liebig, Jennifer Loske, Naveed Ishaque, Uwe G Liebert, Christine Goffinet, Christian Drosten, Sven Laudi, Irina Lehmann, Christian Conrad, Leif E Sander, Roland Eils, Martin Witzenrath
2020-07-14

Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing

David B Blumenthal, Tim Kacprowski, Markus List, Andreas Pichlmair, Tim Daniel Rose, Julian Späth, Kevin Yuan, Jan Baumbach, Nina K Wenke, Julian Matschinske, Josch Pauling
2020-02-06

Genetic screens in isogenic mammalian cell lines without single cell cloning

Mudra Hegde, Christine Strand, John G Doench
2020-07-29

Combined Proteomic and Genetic Interaction Mapping Reveals New RAS Effector Pathways and Susceptibilities

Kaja Kostyrko, Kyuho Han, Edwin E Jeng, Phuong T Dinh, Keene L Abbott
2019-02-12

Human coronaviruses OC43 and HKU1 bind to 9--acetylated sialic acids via a conserved receptor-binding site in spike protein domain A

Geert-Jan Boons, Frank J. M. van Kuppeveld, Berend Jan Bosch
2019-01-16

The ER membrane protein complex promotes biogenesis of sterol-related enzymes maintaining cholesterol homeostasis

Norbert Volkmar, Szymon Juszkiewicz, Daniel Nomura, Ramanujan Shankar Hegde, Benedikt M. Kessler, John C Christianson
2019-12-17

Mechanisms and regulation of cholesterol homeostasis

Jie Luo, Hongyuan Yang, Bao-Liang Song
2019-06-06

Comprehensive Integration of Single-Cell Data

Tim Stuart, Rahul Satija, Christoph Hafemeister, William M. Mauck III, Andrew Butler, Paul J Hoffman, Marlon Stoeckius, Peter Smibert, Efthymia Papalexi
2017-08-07

Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens

Traver Hart, Jolanda S van Leeuwen, Michael Aregger, Sahil Seth, Jason Moffat
2017-10-01

Accessing the Phenotype Gap: Enabling Systematic Investigation of Paralog Functional Complexity with CRISPR.

Stephanie E Mohr, Ben S Ewen-Campen, Norbert Perrimon
2017-05-05

Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens

Oana Ursu, Evan A Boyle, Anshul Kundaje, William Greenleaf
2017-08-29

SREBP-regulated lipid metabolism: convergent physiology - divergent pathophysiology.
2017-12-04

Am I ready for CRISPR? A user's guide to genetic screens.

John G Doench
2016-01-18

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.

Mudra Hegde, Meagan E Sullender, Craig B Wilen, Herbert W. Virgin, David E Root, John G Doench, Robert C Orchard
2016-06-17

A CRISPR screen defines a signal peptide processing pathway required by flaviviruses

Michael S. Diamond, Estefania Fernandez, Rong Zhang, Holly Ramage, Kimberly A Dowd, Jonathan J Miner, Sara Cherry, Matthew J. Gorman, Theodore C Pierson, Adam Zuiani
2016-04-04

Near-optimal probabilistic RNA-seq quantification

Lior Pachter, Harold Pimentel, Páll Melsted
2016-06-17

Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens

Karim Majzoub, Yaw Shin Ooi, Gabriele Fuchs, Kavya Swaminathan, Jan E Carette
2015-12-30

Differential analyses for RNA-seq: transcript-level estimates improve gene-level inferences

Mark D. Robinson, Michael I Love, Charlotte Soneson
2015-03-01

Hepatitis C virus RNA functionally sequesters miR-122

Joseph M Luna, Troels K Scheel, Robert B. Darnell, Charles M. Rice
2015-04-20

limma powers differential expression analyses for RNA-sequencing and microarray studies

Matthew E Ritchie, Belinda Phipson, Gordon K Smyth
2015-10-15

Identification and characterization of essential genes in the human genome

Timothy C Wang, David M. Sabatini, Eric Lander, Kıvanç Birsoy
2015-07-16

A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks

Aviv Regev, Rahul Satija, Nir Hacohen, Itay Tirosh, Raktima Raychowdhury, Dariusz Przybylski, Neville E Sanjana, Steven A Carr, Chun Jimmie Ye, Thomas Eisenhaure, Philipp Mertins
2015-12-16

Quality control, modeling, and visualization of CRISPR screens with MAGeCK-VISPR.

Myles Brown, Wei Li, Johannes Köster
2014-01-01

MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens

Wei Li, Michael I Love, Myles Brown, Rafael Irizarry
2013-01-24

Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol

Benhur Lee, Genhong Cheng, Olivier Pernet, Alexander N. Freiberg, Jerome A Zack

Article - wd:Q99552320

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