Brendan Crabb

1966 -

country of citizenship: Australia

award received: Fellow of the Australian Academy of Health and Medical Sciences, David Syme Research Prize, Companion of the Order of Australia, Fellow of the Australian Academy of Science

Brendan Scott Crabb FASM (born 13 September 1966) is an Australian microbiologist, research scientist and director and chief executive officer of the Burnet Institute, based in Melbourne, Victoria, Australia. Source: Wikipedia (en)

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Articles 129

Date

Title

Authors

2018-09

Plasmepsin V cleaves malaria effector proteins in a distinct endoplasmic reticulum translocation interactome for export to the erythrocyte

Michał Pasternak, Justin A Boddey, Alan Frederick Cowman, Brendan Crabb, Tony Triglia, Danushka S Marapana, Paul R Gilson
2018

Knockdown of the translocon protein EXP2 in Plasmodium falciparum reduces growth and protein export

Brendan Crabb, Paul R Gilson
2018-12-14

Effectiveness of repellent delivered through village health volunteers on malaria incidence in villages in South-East Myanmar: a stepped-wedge cluster-randomised controlled trial protocol

James Beeson, Freya Fowkes, Brendan Crabb
2017-11-20

Functional conservation of the AMA1 host-cell invasion ligand between P. falciparum and P. vivax: a novel platform to accelerate vaccine and drug development.

James Beeson, Brendan Crabb, Paul R Gilson
2017-10-30

Development of a Novel CD4+ TCR Transgenic Line That Reveals a Dominant Role for CD8+ Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria.

Tania F. de Koning-Ward, Ashraful Haque, William R Heath, Daniel Fernandez Ruiz, Claerwen M Jones, Wei Yi Ng, Gayle M Davey, Dorothée L Berthold, Lauren Holz, Yu Kato, Ganchimeg Bayarsaikhan, Sanne H Hendriks, Lianne Lansink, Megan S F Soon, Kylie R James, Vanessa Mollard, Christopher J Tonkin, Tsuneyasu Kaisho, Geoffrey Ian McFadden, Brendan Crabb, Francis Carbone, Lei Shong Lau, Paul R Gilson
2017-03-02

Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate

Anubhav Srivastava, Tania F. de Koning-Ward, Scott A Chisholm, Darren J Creek, Brendan Crabb, Greta E Weiss, Paul R Gilson
2017-01-12

Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity

Craig Hutton, Brad E Sleebs, Sandra Duffy, Vicky M. Avery, Alan Frederick Cowman, Brendan Crabb, Jonathan B Baell, Paul R Gilson
2017-07-21

The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites

Julian Rayner, Matthew Berriman, Lia Chappell, Adam J Blanch, Sarah C. Charnaud, Eric Hanssen, James Beeson, Brendan Crabb, Paul R Gilson
2016-10-13

Disrupting the allosteric interaction between the Plasmodium falciparum cAMP-dependent kinase and its regulatory subunit

Jamie Rossjohn, Travis Beddoe, Dene Littler, Brendan Crabb, Paul R Gilson
2016-11

Proteomic analysis reveals novel proteins associated with the Plasmodium protein exporter PTEX and a loss of complex stability upon truncation of the core PTEX component, PTEX150

Steven Batinovic, Sarah C. Charnaud, Thomas Nebl, Brendan Crabb, Brendan Elsworth, Tania F. de Koning-Ward, Paul R Gilson
2016-11-08

Trafficking of the exported P. falciparum chaperone PfHsp70x

Brendan Crabb, Michael Lanzer, Paul R Gilson
2016-02-01

Recruitment of Factor H as a Novel Complement Evasion Strategy for Blood-Stage Plasmodium falciparum Infection

Wai-Hong Tham, Alan Frederick Cowman, Brendan Crabb, Greta E Weiss, Paul R Gilson, Paul N. Barlow
2016-11-22

Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparum

Brendan Crabb, Brendan Elsworth, Paul R Gilson
2016-06-28

Host cell remodelling in malaria parasites: a new pool of potential drug targets

Tania F. de Koning-Ward, Scott A Chisholm, Brendan Crabb, Paul R Gilson
2016-01-06

Overlaying Molecular and Temporal Aspects of Malaria Parasite Invasion

Brendan Crabb, Greta E Weiss, Paul R Gilson
2016-11-11

Differing rates of antibody acquisition to merozoite antigens in malaria: implications for immunity and surveillance

David L. Narum, Kevin Marsh, James Beeson, Freya Fowkes, Thomas Williams, Brendan Crabb, Robin Fredric Anders, Paul R Gilson, Linda Reiling
2016-10-04

Hierarchical phosphorylation of apical membrane antigen 1 is required for efficient red blood cell invasion by malaria parasites

Conrad Kunick, Christian Doerig, Brendan Crabb, Paul R Gilson
2016-03-28

Exploration of 3-methylisoquinoline-4-carbonitriles as protein kinase A inhibitors of Plasmodium falciparum

Belinda Abbott, Brendan Crabb, Paul R Gilson
2016-04-22

Antimalarial activity of novel 4-cyano-3-methylisoquinoline inhibitors against Plasmodium falciparum: design, synthesis and biological evaluation

Dene Littler, Belinda Abbott, Brendan Crabb, Greta E Weiss, Paul R Gilson
2015-06-10

A Plasmodium Falciparum Bromodomain Protein Regulates Invasion Gene Expression

Zbynek Bozdech, Michaela Petter, Gabrielle A Josling, Thomas Schubert, Danny W Wilson, Michael Duffy, Gernot Längst, Brendan Crabb, Graham V. Brown, Paul R Gilson
2015-12

Plasmodium falciparum Adhesins Play an Essential Role in Signalling and Activation of Invasion into Human Erythrocytes

Wai-Hong Tham, Alan Frederick Cowman, Christian Doerig, Brendan Crabb, Greta E Weiss, Paul R Gilson, Sash Lopaticki
2015-02

Revealing the sequence and resulting cellular morphology of receptor-ligand interactions during Plasmodium falciparum invasion of erythrocytes

Julian Rayner, Wai-Hong Tham, Gavin J. Wright, Freya Fowkes, Alan Frederick Cowman, Brendan Crabb, Greta E Weiss, Paul R Gilson, Paul N. Barlow
2015-07-18

Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum

Fiona Angrisano, Danny W Wilson, Jake Baum, James Beeson, Brendan Crabb, Geoffrey Ian McFadden, Greta E Weiss, Paul R Gilson
2015-12-09

Contrasting Patterns of Serologic and Functional Antibody Dynamics to Plasmodium falciparum Antigens in a Kenyan Birth Cohort

David L. Narum, James Beeson, Alan Frederick Cowman, Brendan Crabb, James W Kazura, Evelina Angov
2015-06-01

Advances in molecular genetic systems in malaria

Tania F. de Koning-Ward, Brendan Crabb, Paul R Gilson
2015-02-01

Why Australia needs a Medical Research Future Fund

Anthony L. Cunningham, Doug Hilton, Brendan Crabb
2014-05

Conditional expression of apical membrane antigen 1 in Plasmodium falciparum shows it is required for erythrocyte invasion by merozoites

Mauro F Azevedo, Danny W Wilson, Alan Frederick Cowman, Brendan Crabb, Greta E Weiss, Paul R Gilson
2014

Plasmodium falciparum transfected with ultra bright NanoLuc luciferase offers high sensitivity detection for the screening of growth and cellular trafficking inhibitors

Mauro F Azevedo, Sarah C. Charnaud, Brendan Crabb, Brendan Elsworth, Paul R Gilson
2014-07-31

PTEX is an essential nexus for protein export in malaria parasites

Mauro F Azevedo, Sarah C. Charnaud, Tania F. de Koning-Ward, Stephen J. Rogerson, Scott A Chisholm, James Beeson, Brendan Crabb, Brendan Elsworth, Paul R Gilson
2014-05-22

CD8+ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria

Anthony T. Papenfuss, Claerwen M Jones, Gayle M Davey, Ashraful Haque, Tania F. de Koning-Ward, Christian R. Engwerda, Scott R Burrows, William R Heath, Michelle A Neller, John Miles, Brendan Crabb, Geoffrey Ian McFadden, Daniel Fernandez Ruiz, Diana S Hansen, Francis Carbone, Lei Shong Lau, Catherine Q Nie
2014-01-27

Protein export in malaria parasites: an update

Brendan Crabb, Brendan Elsworth, Paul R Gilson
2014-08-23

Insights and controversies into the role of the key apicomplexan invasion ligand, Apical Membrane Antigen 1.

Alan Frederick Cowman, Brendan Crabb, Paul R Gilson

Human - wd:Q16196411

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