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Modulation of neurodegeneration by molecular chaperones

published in: Nature Reviews Neuroscience

date of publication: 2005-01-01

language: English

main subject: molecular chaperones

Cites articles 120

Date

Title

Authors

2004-10-14

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
2004-02-01

Heat shock protein 70 participates in the neuroprotective response to intracellularly expressed beta-amyloid in neurons
2004-02-12

Binding of tau to heat shock protein 27 leads to decreased concentration of hyperphosphorylated tau and enhanced cell survival

Kenneth S. Kosik, Hideki Shimura
2004-04-01

CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation

Alexis K Hall, Jungsu Kim, Dennis W. Dickson, Leonard Petrucelli, John Anthony Hardy, Ted M. Dawson, Heather M Snyder
2004-02-06

CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival,CHIP-Hsc70 Complex Ubiquitinates Phosphorylated Tau and Enhances Cell Survival

Steven P. Gygi, Kenneth S. Kosik, Hideki Shimura
2004-03-25

Hsp70 Reduces alpha-Synuclein Aggregation and Toxicity

Eliezer Masliah, Bradley Hyman
2004-08-27

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

Ana María Cuervo
2004-04-28

Progressive decrease in chaperone protein levels in a mouse model of Huntington's disease and induction of stress proteins as a therapeutic approach

Ruben Mestril, Gillian Bates, Michael S. Marber
2004-04-14

Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation

Gijs van Haaften
2004-11-14

Hsp70 and Hsp40 attenuate formation of spherical and annular polyglutamine oligomers by partitioning monomer

Mehmet Sarikaya
2004-07-01

Cellular toxicity of polyglutamine expansion proteins: mechanism of transcription factor deactivation

Manajit Hayer-Hartl, Franz-Ulrich Hartl, Katja Siegers
2004-10

Mechanism of prion propagation: amyloid growth occurs by monomer addition

Sean R Collins, Jonathan Weissman, Ronald Vale
2004-01-18

Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease
2004-04-01

Molecular chaperones and the stress of oncogenesis.
2004-04

Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice

Geoffrey Burnstock
2004-05-20

Hsp104 catalyzes formation and elimination of self-replicating Sup35 prion conformers.

James Shorter, Susan Lindquist
2004-05-02

Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy

Michaela Auer-Grumbach, Ludo Van Den Bosch, Kevin Talbot, Wim Robberecht
2004-06

Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy

Nathalie Verpoorten, Christine Van Broeckhoven, Els De Vriendt, Albena Jordanova, Peter De Jonghe, Wim Robberecht, Vincent Timmerman, An Jacobs, Veerle Van Gerwen, Joy Irobi, Ines Dierick, Ludo Van Den Bosch, Katrien Van Impe, Jan Gettemans, Kevin Talbot
2004-02-01

Roles of molecular chaperones in protein misfolding diseases

Franz-Ulrich Hartl
2004-05-07

Cross-linking of ubiquitin, HSP27, parkin, and alpha-synuclein by gamma-glutamyl-epsilon-lysine bonds in Alzheimer's neurofibrillary tangles
2003-12-18

Protein folding and misfolding

Chris Dobson
2003-04-01

Aggresomes protect cells by enhancing the degradation of toxic polyglutamine-containing protein

Silva Markovic-Plese
2003

Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders
2003-04-18

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
2003-04-07

Expression of the molecular chaperone Hsp70 in detergent-resistant microdomains correlates with its membrane delivery and release

Germain Trugnan, Joëlle Masliah
2003-09-22

Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein

Nigel Mark Hooper
2003-07-18

Presenilin-1, nicastrin, amyloid precursor protein, and gamma-secretase activity are co-localized in the lysosomal membrane,Presenilin-1, Nicastrin, Amyloid Precursor Protein, and γ-Secretase Activity Are Co-localized in the Lysosomal Membrane

Stephen Pasternak
2003-09-01

Evolving questions and paradigm shifts in endoplasmic-reticulum-associated degradation (ERAD).

Ardythe A. McCracken
2003-01-09

Chaperones increase association of tau protein with microtubules

Paul Greengard, Gunnar K. Gouras, Franz-Ulrich Hartl
2003-07-01

High threshold for induction of the stress response in motor neurons is associated with failure to activate HSF1
2003-05-16

Regulation of aging and age-related disease by DAF-16 and heat-shock factor,Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor
2003-09-01

Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila

Article - wd:Q35990274

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