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PALB2 links BRCA1 and BRCA2 in the DNA-damage response

published in: Current Biology

date of publication: 2009-03-05

language: English

main subject: DNA damage

Cites articles 29

Date

Title

Authors

2007-09-04

Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins
2007-04-17

Analysis of PALB2/FANCN-associated breast cancer families

Alan Ashworth, Atilla Ömeroğlu, William David Foulkes, Jorge Reis-Filho, Steven A. Narod, Marc Tischkowitz
2007-02

PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene

Nazneen Rahman, Gareth Evans, Lesley McGuffog, Diana Eccles, Douglas F. Easton, Michael Stratton, Anthony Renwick, Deborah Thompson
2007-07-30

Activation of BRCA1/BRCA2-associated helicase BACH1 is required for timely progression through S phase
2007-02-07

A recurrent mutation in PALB2 in Finnish cancer families.

Anne Kallioniemi, Juha Kere, Lauri Aaltonen, Vesa Kataja, Ronny Drapkin, Katri Pylkäs, Arto Mannermaa, Johanna Schleutker, Ylermi Soini, Arja Jukkola-Vuorinen, Veli-Matti Kosma, Robert Winqvist, Daniel Haber
2006-12-31

Fanconi anemia is associated with a defect in the BRCA2 partner PALB2.

Gerard Pals, Éliane Gluckman
2006-12-31

Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer

Christopher G. Mathew, Nazneen Rahman, Arleen D. Auerbach, Heidemarie Neitzel, Detlev Schindler, Marc Tischkowitz, Helmut Hanenberg, Kornelia Neveling
2006-06-01

Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

Fergus J. Couch
2005-09-01

BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ.
2005-08-21

The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia

John Petrini, Orna Levran, Paula Río, Arleen D. Auerbach, Detlev Schindler
2005-09

The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J

Gerard Pals, Christopher G. Mathew, Quinten Waisfisz, Barbara C Godthelp, Elhaam Elghalbzouri-Maghrani, Fré Arwert, Małgorzata Z Zdzienicka, Martin A Rooimans, Hans Joenje, Wouter W Wiegant
2005-09-01

Unraveling the Fanconi anemia-DNA repair connection
2004-02-01

The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations

Ronny Drapkin
2003-11

Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair

Andrew K Godwin, Mohamed-Ali Hakimi, Ramin Shiekhattar
2003-06

Molecular views of recombination proteins and their control

Stephen C. West
2002-06-13

Biallelic inactivation of BRCA2 in Fanconi anemia

Markus Grompe, Gerard Pals
2002-01-25

Cancer susceptibility and the functions of BRCA1 and BRCA2
2002-08-01

Phosphorylation of serine 1387 in Brca1 is specifically required for the Atm-mediated S-phase checkpoint after ionizing irradiation
2001-05-01

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation
2001-05-18

Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment using phospho-specific antibodies
2001-02-01

BRCA2 is required for homology-directed repair of chromosomal breaks

Mary Ellen Moynahan
2000-12-01

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress
2000-11-23

In search of the tumour-suppressor functions of BRCA1 and BRCA2
2000-06-15

Role for ATM in DNA damage-induced phosphorylation of BRCA1
1999-12

Genetic analysis of BRCA1 function in a defined tumor cell line
1999-11-05

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks
1999-10

Brca1 controls homology-directed DNA repair
1998-09

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

Fergus J. Couch
1998-08-01

Characterization of a breast cancer cell line derived from a germ-line BRCA1 mutation carrier

Article - wd:Q37361223

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