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Genetics and Genomics of Coronary Artery Disease

author

Thomas Quertermous

Milos Pjanic

published in: Current cardiology reports

date of publication: 2016-10-01

language: English

main subject: genomics

Cites articles 110

Date

Title

Authors

2015-10-01

From Locus Association to Mechanism of Gene Causality: The Devil Is in the Details

Thomas Quertermous, Milos Pjanic
2015-09-16

BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

Matthew C Canver, Luca Pinello, Neville E Sanjana, Patrick G Schupp, Sara P Garcia, Sidinh Luc, Ryo Kurita
2015-09-14

WASP: allele-specific software for robust molecular quantitative trait locus discovery

Jonathan K. Pritchard
2015-10

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

Stella Trompet, Eric Boerwinkle, Stavroula Kanoni, Thomas Quertermous, Vilmundur Gudnason, Abbas Dehghan, Andres Metspalu, Tõnu Esko, Panos Deloukas, Samuli Ripatti, Terho Lehtimäki, George Dedoussis, Winfried März, Leo-Pekka Lyytikäinen, Veikko Salomaa, Maria Grazia Franzosi, Markus Perola, Christian Gieger, Danish Saleheen, Anders Hamsten, Albert Hofman, Erik Ingelsson, Richa Saxena, Thomas Meitinger, Olle Melander, Martin Farrall, Heribert Schunkert, Roberto Elosua, Christian Hengstenberg, Jeanette Erdmann, Cecilia Lindgren, Omri Gottesman, Hong-Hee Won, Theodosios Kyriakou, Wei Zhao, Dominique Gauguier, Ilja Demuth, Themistocles L Assimes, Alexandre F. Stewart, Juha Sinisalo, Marcus E Kleber, Patrik K E Magnusson, Albert V. Smith, Hugh Christian Watkins, Annette Peters, Colin Palmer, Pierre Zalloua, Alanna Morrison, Inke R. König, Muredach P. Reilly, Oscar H Franco, Maris Alver, Christopher P Nelson, Alison H Goodall, Christopher B. Granger, Tamara B. Harris, Nilesh Samani, Ruth J. Loos, Erwin Böttinger, Joachim Thiery, Sekar Kathiresan, Lars Lind, Stefan Gustafsson, Julie E. Buring, Ingrid B Borecki, Paul Ridker, Nora Franceschini, Mary Feitosa, Daniel I Chasman, Evelin Mihailov, Lynda M Rose, Jaspal Kooner, André Uitterlinden, J Wouter Jukema, David J Stott, John Danesh, Daniel Rader, L. Adrienne Cupples, Christopher J O'Donnell, Nancy Pedersen, Anuj Goel, Thorsten Kessler, Mariza de Andrade, Elias L Salfati, Bok-ghee Han, Wolf Lieb, Rory Edwards Collins, Alistair Scott Hall, Jean-Paul P.M. de Vries, Jemma C Hopewell, Andrew Bjonnes, Kyoung Yun Kim, Natalia Pervjakova, Markus Scholz, Frank Beutner, Svati H Shah, Diego Ardissino, Stanley L Hazen, Dharambir K Sanghera, Udo Seedorf, Ruth McPherson, Leanne M Hall, Loukianos S Rallidis, Iftikhar J Kullo, John F Thompson, Natalie R van Zuydam, Majid Nikpay, Christina Willenborg, Lingyao Zeng, King Wai Lau, Sonia Anand, Lars Bertram, Philippe Frossard, Marja-Liisa Lokki, Asif Rasheed, Carlos Iribarren, Stephen Schwartz, Emmi Tikkanen, Sebastian M Armasu, Kathleen Stirrups, Lars Lannfelt, Andrew P Morris, Ian Ford, John Campbell Chambers, Yingchang Lu
2015-08-27

Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions

Gavin Sherlock, Alicia N Schep, William Greenleaf, Jason D. Buenrostro
2015-07-01

Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci

Barbara E. Stranger, Kamil Slowikowski, Robert J Klein, Soumya Raychaudhuri, Buhm Han
2015-06-17

Single-cell chromatin accessibility reveals principles of regulatory variation

William Greenleaf, Jason D. Buenrostro
2015-06-01

Adapt-Mix: learning local genetic correlation structure improves summary statistics-based analyses

Noah Zaitlen, Esteban Burchard, Celeste Eng
2015-05

Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap

Sylvia T Nurnberg, Juyong Brian Kim, Ivan Carcamo-Oribe, Vivek Nanda, Ulf Hedin, Lars Maegdefessel, Michelle D Tallquist, Milos Pjanic, Gary K Owens
2015-05-28

Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci

Sylvia T Nurnberg, Juyong Brian Kim, Anshul Kundaje, Themistocles L Assimes, Milos Pjanic, Gill Bejerano
2015-04-02

Myocardial Infarction-Associated SNP at 6p24 Interferes With MEF2 Binding and Associates With PHACTR1 Expression Levels in Human Coronary Arteries

Sekar Kathiresan, Hong-Hee Won, Jean-Claude Tardif
2015-04-02

Lipid-induced epigenomic changes in human macrophages identify a coronary artery disease-associated variant that regulates PPAP2B Expression through Altered C/EBP-beta binding

Elizabeth Soilleux, Susan Smyth
2015-03-27

Assessing allele-specific expression across multiple tissues from RNA-seq read data

Tuuli Lappalainen, Matti Pirinen, Mark McCarthy, Peter Donnelly
2015-03-26

Modulators of hepatic lipoprotein metabolism identified in a search for small-molecule inducers of tribbles pseudokinase 1 expression

Clary B Clish
2015-03-23

Sensitive detection of chromatin-altering polymorphisms reveals autoimmune disease mechanisms

Martin L. Hibberd, Chiea Chuen Khor, Shyam Prabhakar
2015-02-19

Integrative analysis of 111 reference human epigenomes

Ronald Harris
2015-02-19

Genetic and epigenetic fine mapping of causal autoimmune disease variants

Markus Kleinewietfeld, Nikolaos A. Patsopoulos, Mark Joseph Daly, David A. Hafler, Philip L De Jager, Vijay Kuchroo, Bradley Bernstein
2014-12-28

CDH13 promoter SNPs with pleiotropic effect on cardiometabolic parameters represent methylation QTLs

Maris Laan, Silva Kasela, Lili Milani, Viktor Kožich, Elin Org
2014-12-17

RNA-Seq identifies novel myocardial gene expression signatures of heart failure

Yichuan Liu
2014-10-30

Integrating functional data to prioritize causal variants in statistical fine-mapping studies

Bogdan Pasaniuc, Eleazar Eskin, Alkes Price, Sara Lindstroem
2014-08-07

MBASED: allele-specific expression detection in cancer tissues and cell lines

Jinfeng Liu
2014-10-01

Expanding the genetic editing tool kit: ZFNs, TALENs, and CRISPR-Cas9.
2014-09-30

Functional annotation of colon cancer risk SNPs

Peggy Farnham, Benjamin P Berman
2014-09-18

Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels

Nicholas E Banovich, John D Blischak, Yoav Gilad, Jonathan K. Pritchard
2014-08-24

The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance

Danielle Thierry-Mieg, Michele Filosi, Roberto Visintainer, Florian Caiment, Samantha Riccadonna, Marco Chierici, Lee Lancashire, Binsheng Gong, Davide Albanese, Jean Thierry-Mieg, Giuseppe Jurman, Jos Kleinjans, Weida Tong, Leming Shi, Paweł P Łabaj, Youping Deng, Andreas Scherer, Richard Paules, Huixiao Hong, James C Fuscoe, Cesare Furlanello, Marina Bessarabova, Dalila B Megherbi, Pierre R Bushel, David P Kreil
2014-07-28

A novel role of CDX1 in embryonic epicardial development

Richard Mailman
2014-07-18

Developmental heterogeneity of cardiac fibroblasts does not predict pathological proliferation and activation

Kristy Red-Horse
2014-07-17

Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease.

Heribert Schunkert, Jeanette Erdmann, Thomas Quertermous, Mete Civelek, Ville-Petteri Mäkinen, Sujoy Ghosh, Themistocles L Assimes, Muredach P. Reilly, Aldons Jake Lusis, Nilesh Samani, Christopher P Nelson, Winfried März, Sekar Kathiresan
2014-06-26

Integrative DNA, RNA, and protein evidence connects TREML4 to coronary artery calcification

NISC Comparative Sequencing Program, Leslie G Biesecker, Eric D. Green, James C Mullikin, Andrew E Arai, Frank D Kolodgie, Renu Virmani, Patricia A Peyser, Christopher J O'Donnell, Lila Adams
2014-06-10

Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing

Chad A. Cowan
2014-05-20

A Bayesian method to incorporate hundreds of functional characteristics with association evidence to improve variant prioritization

Sarah A Gagliano, Michael R. Barnes, Michael E. Weale, Jo Knight
2014-03-27

Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation

Heribert Schunkert, Jeanette Erdmann, Thomas Quertermous, Lars Maegdefessel, Themistocles L Assimes, Ulf Hedin

Article - wd:Q38944185

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