Nicol Keith

occupazione: ricercatore

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Articoli 59

Data

Titolo

Autori

2017-03-31

Extensive telomere erosion is consistent with localised clonal expansions in Barrett's metaplasia

Nicol Keith, Gareth J Jenkins, Duncan Baird
2017-08-14

A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds

Claire J. Cairney, Sharon Burns, Lynn McGarry, John Revie, Elpida Tsonou, Dorothy Bennett, Masashi Narita, Nicol Keith
2015-03-06

Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds

Thomas E. Carey, Jin-Tang Dong, Gloria S Huang, Kanya Honoki, Alexandros G Georgakilas, Amedeo Amedei, Chandra S Boosani, Nicol Keith, Katia Aquilano, Syed Ashraf, Alan E. Bilsland
2015-12-01

Broad targeting of angiogenesis for cancer prevention and therapy

Zongwei Wang, Ganji Purnachandra Nagaraju, Alexandros G Georgakilas, Amedeo Amedei, Syed Ashraf, Gunjan Guha, Katia Aquilano, Alan E. Bilsland, Nicol Keith, Lasse D Jensen, W. Kimryn Rathmell, Domenico Ribatti
2015-12-01

Therapeutic targeting of replicative immortality

Karen MacKenzie, Nicol Keith, Francis Rodier, Amancio Carnero, Alan E. Bilsland, Kanya Honoki, Alexandros G Georgakilas, Amedeo Amedei, Chandra S Boosani, Gunjan Guha, Katia Aquilano, Syed Ashraf
2015-07-01

Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition

Claire J. Cairney, Andrew R J Young, Nicol Keith, Dorothy Bennett
2015-05-05

A multi-targeted approach to suppress tumor-promoting inflammation

Alan E. Bilsland, Alexandros G Georgakilas, Amedeo Amedei, Carolina Panis, Chandra S Boosani, Gunjan Guha, Kanya Honoki, Katia Aquilano, Luigi Ricciardiello, Syed Ashraf, Nicol Keith, Amr Amin, Asfar S Azmi, Leroy Lowe, Somaira Nowsheen, Sulma I Mohammed, Dipita Bhakta
2015-04-17

Sustained proliferation in cancer: Mechanisms and novel therapeutic targets

Mark A. Feitelson, Maria Luz Martinez Chantar, Isidro Sanchez-garcia, Kanya Honoki, Alexandros G Georgakilas, Amedeo Amedei, Syed Ashraf, Chandra S Boosani, Gunjan Guha, Katia Aquilano, Nicol Keith
2015-12-01

Designing a broad-spectrum integrative approach for cancer prevention and treatment

Amedeo Amedei, Katia Aquilano, Syed Ashraf, Chandra S Boosani, Amancio Carnero, Marisa Connell, Jin-Tang Dong, Eyad Elkord, Christian Frezza, Alexandros G Georgakilas, Frank Gieseler, Petr Heneberg, Matthew D. Hirschey, Kanya Honoki, Lasse D Jensen, Wen G. Jiang, Nicol Keith, Anne Le, Jason W. Locasale, Costas A Lyssiotis, Karen MacKenzie, Maria Luz Martinez Chantar, Christopher A Maxwell, Michael P. Murphy, Ganji Purnachandra Nagaraju, Carolina Panis, Francesco Pantano, S Prakash, Lizzia Raffaghello, Luigi Ricciardiello, R. Brooks Robey, Francis Rodier, Gian Luigi Russo, Isidro Sanchez-garcia, Emanuela Signori, Sharanya Sivanand, Wamidh H Talib, Phuoc T. Tran, Massimo Zollo, Keith I Block, W. Kimryn Rathmell, Graham Pawelec, Domenico Ribatti, Lynnette Ferguson, Clement G Yedjou, Leroy Lowe, Amr Amin, Asfar S Azmi, Dean W Felsher, Michael Gilbertson, William G Helferich, Randall F. Holcombe, Liang-Tzung Lin, Sulma I Mohammed, Somaira Nowsheen, Swapan K Ray, Dipita Bhakta, Ralph J DeBerardinis, Georgia Zhuo Chen, Daniele Santini, Valter Longo
2015-09-01

Identification of a Selective G1-Phase Benzimidazolone Inhibitor by a Senescence-Targeted Virtual Screen Using Artificial Neural Networks

Claire J. Cairney, Masashi Narita, Nicol Keith
2015-04-11

Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition

Andrew R. Collins, Marisa Connell, Amedeo Amedei, Syed Ashraf, Katia Aquilano, Alan E. Bilsland, Chandra S Boosani, Gunjan Guha, Nicol Keith, Kanya Honoki, Phuoc T. Tran, Christopher A Maxwell, Lynnette Ferguson
2015-04-28

Broad targeting of resistance to apoptosis in cancer

Carmela Fimognari, Gian Luigi Russo, Kanya Honoki, Alexandros G Georgakilas, Amedeo Amedei, Syed Ashraf, Chandra S Boosani, Gunjan Guha, Katia Aquilano, Nicol Keith, Alan E. Bilsland, Clement G Yedjou, Leroy Lowe, Liang-Tzung Lin, Carmela Spagnuolo, Elena Niccolai, William G Helferich, Somaira Nowsheen, Swapan K Ray, Ramzi M Mohammad, Sulma I Mohammed, Asfar S Azmi, Dipita Bhakta, Amr Amin
2015-04-09

Cancer prevention and therapy through the modulation of the tumor microenvironment

Amedeo Amedei, Katia Aquilano, Fabian Benencia, Chandra S Boosani, Alexandros G Georgakilas, Gunjan Guha, Petr Heneberg, Kanya Honoki, Nicol Keith, Wamidh H Talib
2015-03-25

Immune evasion in cancer: Mechanistic basis and therapeutic strategies

Wamidh H Talib, Eyad Elkord, Emanuela Signori, Kanya Honoki, Alexandros G Georgakilas, Chandra S Boosani, Gunjan Guha, Nicol Keith, Katia Aquilano, Syed Ashraf, Graham Pawelec
2015-04-09

Tissue invasion and metastasis: Molecular, biological and clinical perspectives

Wen G. Jiang, Lin Ye, Alan E. Bilsland, Daniele Santini, Frank Gieseler, Sarah K. Thompson, Kanya Honoki, Alexandros G Georgakilas, Amedeo Amedei, Syed Ashraf, Chandra S Boosani, Gunjan Guha, Katia Aquilano, Nicol Keith, Francesco Pantano
2015-01-01

Plasma N-acetyl-glucosaminidase in advanced gastro-intestinal adenocarcinoma correlates with age, stage and outcome

Alan E. Bilsland, Daniel Hartmann, Zhangfa Song, Karl Lenhard Rudolph, Nicol Keith, T. R. Jeffry Evans
2014-02-13

Mathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanisms

Alan E. Bilsland, Claire J. Cairney, Nicol Keith
2014-07-22

Immortalization of T-cells is accompanied by gradual changes in CpG methylation resulting in a profile resembling a subset of T-cell leukemias

Sofie Degerman, Krystyna Chrzanowska, Nicol Keith, Jan Konrad Siwicki
2014-06-03

Isolation, culture, and transfection of melanocytes

Claire J. Cairney, Jaskaren S Kohli, Philip S Goff, Nicol Keith
2012-04-19

Telomere maintenance mechanisms in malignant peripheral nerve sheath tumors: expression and prognostic relevance

Maria Grazia Daidone, Rosita Motta, Alessandro Gronchi, Marco Folini, Nicol Keith, Nadia Zaffaroni
2012-01-31

Cancer cell senescence: a new frontier in drug development

Claire J. Cairney, Alan E. Bilsland, Dorothy Bennett, Masashi Narita, Nicol Keith, T. R. Jeffry Evans
2012-06-01

A small molecule modulator of prion protein increases human mesenchymal stem cell lifespan, ex vivo expansion, and engraftment to bone marrow in NOD/SCID mice.

Claire J. Cairney, Nicol Keith, Ilaria Bellantuono
2011-07-08

Progeroid syndromes: models for stem cell aging?

Ilaria Bellantuono, Nicol Keith
2011-02-01

Targeting the telomere and shelterin complex for cancer therapy: current views and future perspectives

Claire J. Cairney, Alan E. Bilsland, Nicol Keith
2011-08-30

Mesenchymal stem cells as therapeutic delivery vehicles targeting tumor stroma

Flemming Brandt Sørensen, Frederik Dagnæs-Hansen, Nicol Keith
2010-10-01

Scoring of senescence signalling in multiple human tumour gene expression datasets, identification of a correlation between senescence score and drug toxicity in the NCI60 panel and a pro-inflammatory signature correlating with survival advantage in peritoneal mesothelioma

Alan E. Bilsland, Claire J. Cairney, Nadia Zaffaroni, Karin Oien, Nicol Keith
2010-01-01

Modulation of gene expression using zinc finger-based artificial transcription factors

Alan E. Bilsland, Nicol Keith
2009-07-31

Dynamic telomerase gene suppression via network effects of GSK3 inhibition

Alan E. Bilsland, Claire J. Cairney, Nicol Keith
2009-08-17

A gene expression signature classifying telomerase and ALT immortalization reveals an hTERT regulatory network and suggests a mesenchymal stem cell origin for ALT

Claire J. Cairney, Nadia Zaffaroni, Alan E. Bilsland, Maria Grazia Daidone, Nicol Keith
2009-01-01

A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A.

Irina Neganova, Nicol Keith, Miodrag Stojkovic
2009-08-01

The PTEN regulator DJ-1 is associated with hTERT expression in clear cell renal cell carcinoma.

Claire J. Cairney, Nicol Keith, Börje Ljungberg, Göran Roos
2009-02-06

A systems biology approach to Down syndrome: identification of Notch/Wnt dysregulation in a model of stem cells aging

Claire J. Cairney, Nicol Keith, Maria Cristina Nostro, Ilaria Bellantuono

Human - wd:Q43144511

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