Jean Beggs

1950 -

country of citizenship: United Kingdom

languages spoken, written or signed: English

educated at: University of Edinburgh, University of Glasgow

award received: Fellow of the Royal Society, Commander of the Order of the British Empire, Fellow of the Royal Society of Edinburgh, Novartis Medal and Prize, Gabor Medal

Jean Duthie Beggs CBE FRS FRSE DSc (née Lancaster, born 16 April 1950) is a Scottish geneticist. She is the Royal Society Darwin Trust Professor in the Wellcome Trust Centre for Cell Biology at the University of Edinburgh. Source: Wikipedia (en)

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Articles 52

Date

Title

Authors

2020-05-21

Revisiting the window of opportunity for co-transcriptional splicing in budding yeast

Vahid Aslanzadeh, Jean Beggs
2019-01-23

Mutagenesis of Snu114 domain IV identifies a developmental role in meiotic splicing

Jean Beggs
2019-09-04

Blocking late stages of splicing quickly limits pre-spliceosome assembly in vivo

David Barrass, Jean Beggs
2019-07-09

Spt5 modulates cotranscriptional spliceosome assembly in Saccharomyces cerevisiae

Isabella E Maudlin, Jean Beggs
2019-07-20

Tuning Degradation to Achieve Specific and Efficient Protein Depletion

David Barrass, Jean Beggs
2019-08-22

Extremely Rapid and Specific Metabolic Labelling of RNA In Vivo with 4-Thiouracil (Ers4tU)

David Barrass, Jean Beggs
2018-04-01

Corrigendum: Transcription rate strongly affects splicing fidelity and cotranscriptionality in budding yeast.

Jean Beggs
2018-08-01

A Nuclear Export Block Triggers the Decay of Newly Synthesized Polyadenylated RNA

Agnieszka Tudek, David Barrass, Torben Heick Jensen, Jean Beggs
2018-11-12

A fast and tuneable auxin-inducible degron for depletion of target proteins in budding yeast

David Barrass, Vahid Aslanzadeh, Jane E A Reid, Jean Beggs
2017-02-02

Extremely fast and incredibly close: cotranscriptional splicing in budding yeast

Jean Beggs, Edward Wallace
2017-10-13

RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit.

Laura Milligan, Camille Sayou, Alex Tuck, Jane E A Reid, Robin Campbell Allshire, Christos Spanos, Juri Rappsilber, Grzegorz Kudła, David Tollervey, Jean Beggs
2017-12-18

Transcription rate strongly affects splicing fidelity and cotranscriptionality in budding yeast

Jean Beggs, Vahid Aslanzadeh, Yuanhua Huang
2015-12-17

Transcriptome-wide RNA processing kinetics revealed using extremely short 4tU labeling

Ralph D Hector, Sander Granneman, David Barrass, Jane E A Reid, Yuanhua Huang, Jean Beggs
2015-03-03

Cwc21p promotes the second step conformation of the spliceosome and modulates 3' splice site selection

David Barrass, Jean Beggs
2014-02-20

A splicing-dependent transcriptional checkpoint associated with prespliceosome formation

David Barrass, Jean Beggs
2014-11-26

Brr2p carboxy-terminal Sec63 domain modulates Prp16 splicing RNA helicase

Cosmin Saveanu, David Barrass, Jean Beggs
2013-01

RNA helicases in splicing

Jean Beggs
2013-03-01

Structural basis for dual roles of Aar2p in U5 snRNP assembly

Reinhard Georg Lührmann, Gert Weber, Markus C Wahl, Jean Beggs
2013-06-26

A rule-based kinetic model of RNA polymerase II C-terminal domain phosphorylation

Jean Beggs
2012-11-01

Brr2p-mediated conformational rearrangements in the spliceosome during activation and substrate repositioning

David Tollervey, Grzegorz Kudła, Jean Beggs
2012-03-29

Structure, function and regulation of spliceosomal RNA helicases

Jean Beggs
2012-10-23

Kinetic analysis of pre-ribosome structure in vivo

Alex Tuck, David Barrass, David Tollervey, Jean Beggs
2011-08-01

Mechanism for Aar2p function as a U5 snRNP assembly factor

Juri Rappsilber, Markus C Wahl, Gert Weber, Jean Beggs
2011-10-13

Modelling reveals kinetic advantages of co-transcriptional splicing

Jean Beggs
2011-05-24

Cross-linking, ligation, and sequencing of hybrids reveals RNA-RNA interactions in yeast

David Tollervey, Sander Granneman, Grzegorz Kudła, Jean Beggs
2010-01-28

Processivity and coupling in messenger RNA transcription

Igor Goryanin, Edouard Bertrand, Jean Beggs
2010-10-25

RiboSys, a high-resolution, quantitative approach to measure the in vivo kinetics of pre-mRNA splicing and 3'-end processing in Saccharomyces cerevisiae

David Barrass, Martin Kos, David Tollervey, Joanna Kufel, Edouard Bertrand, Jean Beggs
2010-08-01

Brr2p RNA helicase with a split personality: insights into structure and function

Jean Beggs
2010-10-01

Cross-talk in transcription, splicing and chromatin: who makes the first call?

Jean Beggs
2010-11-01

Splicing-dependent RNA polymerase pausing in yeast

Jean Beggs
2010-05-01

Prognosis for splicing factor PRPF8 retinitis pigmentosa, novel mutations and correlation between human and yeast phenotypes

Rajkumar Ramesar, David A. Mackey, Graeme Black, Eric A Pierce, Chris F. Inglehearn, Parastoo Ehsani, Jean Beggs
2009-10-23

Physical and genetic interactions of yeast Cwc21p, an ortholog of human SRm300/SRRM2, suggest a role at the catalytic center of the spliceosome

Alain Jacquier, Jean Beggs

Human - wd:Q6170247

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