Debora Marks

photo credits: Wikimedia Commons

educated at: Humboldt University of Berlin

occupation: bioinformatician, biologist

award received: Overton Prize

official website: marks.hms.harvard.edu

Debora S. Marks is a researcher in computational biology and a Professor of Systems Biology at Harvard Medical School. Her research uses computational approaches to address a variety of biological problems. Source: Wikipedia (en)

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Articles 70

Date

Title

Authors

2023-08-02

Scientific discovery in the age of artificial intelligence

Shengchao Liu, Carla Gomes, Pushmeet Kohli, Jure Leskovec, Debora Marks, Connor W. Coley, Yoshua Bengio, Marinka Žitnik
2021-04-23

Protein design and variant prediction using autoregressive generative models

Aashish Manglik, Andrew C Kruse, Debora Marks
2020-03-09

Structural coordination of polymerization and crosslinking by a SEDS-bPBP peptidoglycan synthase complex

Kelly P Brock, Atsushi Taguchi, Suzanne Walker, Thomas G Bernhardt, Andrew C Kruse, Debora Marks
2020-05-11

Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact

Melissa A Chiasson, Frederick P. Roth, Debora Marks, Douglas M Fowler, Marta Verby
2020-09-01

Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact

Melissa A Chiasson, Debora Marks, Douglas M Fowler, Marta Verby
2020-11-11

Rapid generation of potent antibodies by autonomous hypermutation in yeast

Alon Wellner, Conor McMahon, Jung-Eun Shin, Jared Feldman, Blake M Hauser, Timothy M Caradonna, Laura M Wingler, Aaron G Schmidt, Debora Marks, Andrew C Kruse, Chang C Liu
2020-12-21

CellBox: Interpretable Machine Learning for Perturbation Biology with Application to the Design of Cancer Combination Therapy

Chris Sander, Debora Marks
2019-05-01

The EVcouplings Python framework for coevolutionary sequence analysis

Anna G Green, Christian Dallago, Chris Sander, Debora Marks, Robert Sheridan, Thomas A Hopf, Agnes Toth-Petroczy
2019-12-11

Protein Structure from Experimental Evolution

Chris Sander, Debora Marks
2019-08-20

Interaction specificity of clustered protocadherins inferred from sequence covariation and structural analysis

John M Nicoludis, Anna G Green, Marcos Sotomayor, Rachelle Gaudet, Debora Marks
2019-06-17

Inferring protein 3D structure from deep mutation scans

Frank J Poelwijk, Debora Marks, Chris Sander
2018-03-02

Population-specific design of de-immunized protein biotherapeutics

Oliver Kohlbacher, Benjamin Schubert, Pierre Dönnes, Debora Marks, Thomas A Hopf
2018-03-28

Structure of the peptidoglycan polymerase RodA resolved by evolutionary coupling analysis

Patricia Rohs, Anna G Green, Debora Marks, Thomas A Hopf
2018-06-11

Structure and mutagenic analysis of the lipid II flippase MurJ from Escherichia coli

Lok-To Sham, Andrew C Kruse, Debora Marks
2018-10-16

Cryo-electron microscopy structure of the lipid droplet-formation protein seipin

Xuewu Sui, Tobias C Walther, Debora Marks, Robert V Farese
2018-11-07

Evidence that regulation of intramembrane proteolysis is mediated by substrate gating during sporulation in Bacillus subtilis

Andrew C Kruse, Fernando H Ramírez-Guadiana, Christopher D A Rodrigues, David Z Rudner, Debora Marks
2018-09-06

A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation

Debora Marks, Thomas A Hopf
2018-09-11

Gain-of-function experiments with bacteriophage lambda uncover residues under diversifying selection in nature

Rohan Maddamsetti, Daniel T Johnson, Debora Marks
2018-07-01

A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation

Eran Kotler, Debora Marks, Thomas A Hopf
2018-12-03

Genome-wide discovery of epistatic loci affecting antibiotic resistance in Neisseria gonorrhoeae using evolutionary couplings

Benjamin Schubert, Rohan Maddamsetti, Debora Marks
2018-12-23

Combining Evolutionary Covariance and NMR Data for Protein Structure Determination

Chris Sander, Debora Marks
2018-01-01

A Hybrid Approach for Protein Structure Determination Combining Sparse NMR with Evolutionary Coupling Sequence Data

Chris Sander, Debora Marks
2018-09-24

Deep generative models of genetic variation capture the effects of mutations

Debora Marks
2017-04-04

Core Genes Evolve Rapidly in the Long-term Evolution Experiment with Escherichia coli

Anna G Green, Richard Lenski, Debora Marks
2017-01-16

Mutation effects predicted from sequence co-variation

Chris Sander, Debora Marks, Thomas A Hopf, Michael Springer
2017-07-26

Noise control is a primary function of microRNAs and post-transcriptional regulation

Ben Lehner, Debora Marks
2016-11-15

Genomic Epidemiology of Gonococcal Resistance to Extended-Spectrum Cephalosporins, Macrolides, and Fluoroquinolones in the United States, 2000-2013

Debora Marks, Marc Lipsitch, Anna G Green, Stephen D Bentley
2016-07-29

Antiparallel protocadherin homodimers use distinct affinity- and specificity-mediating regions in cadherin repeats 1-4

Debora Marks, Rachelle Gaudet, Bennett E Vogt, Anna G Green, John M Nicoludis
2016-04-13

3D RNA and Functional Interactions from Evolutionary Couplings

Chris Sander, Debora Marks, Caleb Weinreb
2016-09-01

Structured States of Disordered Proteins from Genomic Sequences

Chris Sander, Bonnie Berger, Debora Marks, Thomas A Hopf, Agnes Toth-Petroczy
2016-03-01

Core Genes Evolve Rapidly in the Long-term Evolution Experiment with Escherichia coli

Debora Marks
2016-07-12

Antiparallel protocadherin homodimers use distinct affinity- and specificity mediating regions in cadherin repeats 1-4

Anna G Green, Rachelle Gaudet, Debora Marks

Human - wd:Q23809228

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